Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line
Identifieur interne : 000E76 ( Istex/Curation ); précédent : 000E75; suivant : 000E77Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line
Auteurs : S. Ablan [États-Unis] ; S. S. Rawat [États-Unis] ; R. Blumenthal [États-Unis] ; A. Puri [États-Unis]Source :
- Archives of Virology [ 0304-8608 ] ; 2001-11-01.
Abstract
Summary.: A glycosphingolipid (GSL)-deficient mouse skin fibroblast mutant cell line (GM95) was tested for its susceptibility to influenza virus infection and/or fusion. Octadecyl rhodamine labeled influenza virus fused at 37 °C and low pH with GM95 cells at similar rates and extents as with the parental cell lines which did bear glycosphingolipids. Influenza virus infected the GM95 cells at the same level as the parental cell lines. The infection and fusion was blocked when the cell lines were pre-treated with neuramindase. We conclude that influenza virus uses mainly sialoglycoproteins and that gangliosides are not essential for influenza virus fusion and infection.
Url:
DOI: 10.1007/s007050170033
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000E76
Links to Exploration step
ISTEX:F4F9019CB170B36C7908E2DBEA2C5265F7506A41Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line</title><author><name sortKey="Ablan, S" sort="Ablan, S" uniqKey="Ablan S" first="S." last="Ablan">S. Ablan</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Rawat, S S" sort="Rawat, S S" uniqKey="Rawat S" first="S. S." last="Rawat">S. S. Rawat</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Blumenthal, R" sort="Blumenthal, R" uniqKey="Blumenthal R" first="R." last="Blumenthal">R. Blumenthal</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Puri, A" sort="Puri, A" uniqKey="Puri A" first="A." last="Puri">A. Puri</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F4F9019CB170B36C7908E2DBEA2C5265F7506A41</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1007/s007050170033</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-GR937DSL-L/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000E76</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E76</idno><idno type="wicri:Area/Istex/Curation">000E76</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line</title><author><name sortKey="Ablan, S" sort="Ablan, S" uniqKey="Ablan S" first="S." last="Ablan">S. Ablan</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Rawat, S S" sort="Rawat, S S" uniqKey="Rawat S" first="S. S." last="Rawat">S. S. Rawat</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Blumenthal, R" sort="Blumenthal, R" uniqKey="Blumenthal R" first="R." last="Blumenthal">R. Blumenthal</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author><author><name sortKey="Puri, A" sort="Puri, A" uniqKey="Puri A" first="A." last="Puri">A. Puri</name><affiliation wicri:level="1"><mods:affiliation>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD, US</mods:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>LECB, CCR, NCI-Frederick, National Institutes of Health, Frederick, MD</wicri:regionArea></affiliation></author></analytic><monogr></monogr><series><title level="j">Archives of Virology</title><title level="j" type="abbrev">Arch. Virol.</title><idno type="ISSN">0304-8608</idno><idno type="eISSN">1432-8798</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Wien</pubPlace><date type="published" when="2001-11-01">2001-11-01</date><biblScope unit="volume">146</biblScope><biblScope unit="issue">11</biblScope><biblScope unit="page" from="2227">2227</biblScope><biblScope unit="page" to="2238">2238</biblScope></imprint><idno type="ISSN">0304-8608</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-8608</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary.: A glycosphingolipid (GSL)-deficient mouse skin fibroblast mutant cell line (GM95) was tested for its susceptibility to influenza virus infection and/or fusion. Octadecyl rhodamine labeled influenza virus fused at 37 °C and low pH with GM95 cells at similar rates and extents as with the parental cell lines which did bear glycosphingolipids. Influenza virus infected the GM95 cells at the same level as the parental cell lines. The infection and fusion was blocked when the cell lines were pre-treated with neuramindase. We conclude that influenza virus uses mainly sialoglycoproteins and that gangliosides are not essential for influenza virus fusion and infection.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E76 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000E76 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Istex
|étape= Curation
|type= RBID
|clé= ISTEX:F4F9019CB170B36C7908E2DBEA2C5265F7506A41
|texte= Entry of influenza virus into a glycosphingolipid-deficient mouse skin fibroblast cell line
}}
| This area was generated with Dilib version V0.6.33. |  |